Lysine to Combat Cold Sores

One of the most frequent requests we receive from readers is for infor- mation on lysine therapy to share with their family and friends who suffer from painful and unsightly mouth sores. Here are the key points:

  • The late Dr. Richard Griffith, a dedicated lysine researcher at Indiana University, recommended that cold sore sufferers take 500 mg of lysine (an amino acid) per 22 pounds of body weight daily. To cal- culate the appropriate dose, divide body weight by 22, then multiply by 500. A person who weighs 132 pounds would take 3,000 mg of lysine each day.
  • Lysine supplements are avail- able without a prescription, and treatment is most effective if begun when symptoms first occur. Look for supplements containing 1-lysine.
  • Lysine probably works best when it is combined with dietary changes that restrict levels of argi- nine, another amino acid. To do this, cut down on gelatin, chocolate, peanuts, and almonds.




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