Posted August 3, 2007
Could getting enough dietary vitamin K help keep osteoarthritis at bay? Study volunteers with the highest blood levels of the main form of vitamin K–phylloquinone–were associated with the lowest risk among participants of having osteoarthritis in the hands and knees. The study was conducted by Agricultural Research Service (ARS)-funded scientists.
Osteoarthritis is a joint disease that involves the breakdown of cartilage and bones, which leads to pain and stiffness.
The lead researcher, Sarah L. Booth, is director of the Vitamin K Laboratory at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University in Boston, Mass. She and Boston University rheumatologist Tuhina Neogi reported the findings in Arthritis & Rheumatism. ARS is the U.S. Department of Agriculture’s chief scientific research agency.
For the study, Booth and colleagues used new methods to assess participants’ vitamin K blood plasma concentrations, as well as associations between that status and osteoarthritis. The study is particularly significant because low dietary intakes of vitamin K are known to be associated with relatively higher amounts of bone loss in the elderly, according to authors.
The researchers have also determined the amount of several major types of vitamin K in hundreds of foods. Through a collaboration, those data and more are available via the ARS Nutrient Data Laboratory website, which is part of the Beltsville Human Nutrition Research Center at Beltsville, Md.